IgG Placental Transfer in Healthy and Pathological Pregnancies
نویسندگان
چکیده
منابع مشابه
IgG Placental Transfer in Healthy and Pathological Pregnancies
Placental transfer of maternal IgG antibodies to the fetus is an important mechanism that provides protection to the infant while his/her humoral response is inefficient. IgG is the only antibody class that significantly crosses the human placenta. This crossing is mediated by FcRn expressed on syncytiotrophoblast cells. There is evidence that IgG transfer depends on the following: (i) maternal...
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ژورنال
عنوان ژورنال: Clinical and Developmental Immunology
سال: 2012
ISSN: 1740-2522,1740-2530
DOI: 10.1155/2012/985646